Ezetimibe may cause side effects. You can use the study as a second opinion to make health care decisions. If your muscle-related side effects dont go away or become severe, tell your doctor right away. Can diet help improve depression symptoms? Learn about side effects, costs. Learn about the drugs dosages, forms, strengths, and more. OI is a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position. Zetia may cause joint pain. This can cause gallstones (hardened stones in your gallbladder). While taking Zetia, tell your doctor right away if you experience extreme muscle pain, muscle tenderness, or dark-colored urine. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. In fact, researchers have looked into using Zetia to treat hair loss due to a condition called alopecia areata. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. The actual price youll pay for any of these drugs depends on your treatment plan, your insurance plan, your location, and the pharmacy you use. Last medically reviewed on September 18, 2021. Temporary excursions of 59F to 86F (15C to 30C) are allowed. Since every POTS patient is different, some may primarily experience gastrointestinal symptoms, such as nausea, vomiting or poor feeding, Berger explained. As with most drugs, some people can have an allergic reaction after taking Zetia. 4. However, studies have found both Zetia and Lipitor to be effective for lowering cholesterol. Theyll likely suggest changes to your treatment plan. If youre experiencing hair loss while using Zetia, talk with your doctor. The insurance company will review the prior authorization request and decide if the drug will be covered. A large review by the American Heart Association compared studies of CoQ10. The following information describes dosages that are commonly used or recommended. If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. Your child can take Zetia with or without food. You can take Zetia with or without food. Your doctor may prescribe Zetia with a statin drug. What are the serious side effects of Zetia? Zetia isnt known to interact with grapefruit or any other foods. You can use the study as a second opinion to make health care decisions. Both drugs are typically taken once each day. Liver problems. Both Zetia and Lipitor come as tablets that are swallowed. They may also check you for signs of muscle breakdown or kidney damage. joint or muscle pain*. Your doctor will likely start you on the typical dosage approved to treat your condition. Talk with your doctor about any liver problems you may have and whether its safe for you to take Zetia. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. We talked to experts about, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. For more information, see the Precautions section below. Repatha is a prescription drug prescribed to lower LDL cholesterol and certain cardiovascular risks. Zetia can cause muscle-related side effects. weakness and fatigue (tiredness) headaches. During Zetia treatment, your doctor will likely recommend blood tests. You should store Zetia tablets at a room temperature of 77F (25C) in a tightly sealed container away from light. They can suggest ways to help relieve this side effect. Zetia may not be right for you if you have certain medical conditions or other factors affecting your health. If you need financial support to pay for Zetia, or if you need help understanding your insurance coverage, help is available. Learn about side effects, dosage, and more. Below are examples of these side effects. Talk with your doctor if you experience diarrhea while taking this medication. Created for people with ongoing healthcare needs but benefits everyone. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. The side effects from Zetia .. muscle weakness, joint pain, upper respiratory infectikns resemble the symptoms of malabsorption of Vitamin A,D, E and K. Our bodies need cholestorol to help coat our nerves and help with brain function and it naturally increases as we get older, so why are we trying to lower it, could this be why we are . Both Zetia and Crestor come as tablets that are swallowed. Youll likely take it once a day. This drug has not been studied in pregnant females.*. Call your doctor right away if you have serious side effects. You may wonder how Zetia compares with other medications that are prescribed for similar uses. The symptoms develop immediately and include dizziness and an intense headache. Zetia is metabolized in the small intestine and liver. If youre concerned about joint pain while using Zetia, talk with your doctor. Other drugs are available that can treat your conditions. Study on Ezetimibe Yielded Disappointing Results: Another reader wrote us shortly after learning of the results of a study that raised questions about ezetimibe: Q. Some side effects are more common than others. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). Mild side effects of Zetia when taken with a statin (another kind of cholesterol -lowering drug) may include: infection, such as a respiratory . You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. POTS-related fatigue is physical in nature . Cardiology 33 years experience. These symptoms can be signs of an infection. Taking Zetia with cholestyramine can decrease the amount of Zetia in your body. You may experience muscle problems as a side effect of Zetia. They may have a preference for one version or the other. Statins are another type of medication used to lower cholesterol. Phil Fischer, M.D., medical director of Mayo Clinic's children's hospital and a POTS specialist, led . When this happens, more cholesterol can then be cleared from your blood by your liver. This includes grapefruit and grapefruit juice. For this purpose, Zetia is used with a low-cholesterol diet and is taken with atorvastatin or simvastatin in adults and in children ages 10 years and older. Crossing your legs in front of each other while standing, rocking up and down on your toes. Allergic reaction. * To learn more about this side effect, see the Side effects explained section below. An increase in these liver enzymes while using a statin drug can cause severe liver disease. For those who aren't familiar with POTS, it is an often-disabling neurological condition that causes your heart rate to rise a great deal when you are upright, and often blood pressure drops when you are upright (when it should be rising), and it causes fainting, fatigue, headache, nausea, face and hand tingling, and blood pooling in legs. The phase IV clinical study analyzes which people take Zetia and have Constipation. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. Muscle problems were reported in clinical studies of adults and children who took Zetia with statin drugs. So stopping Zetia may lead to an increase in your cholesterol levels. In clinical studies that lasted 8 weeks, Zetia was compared with a placebo (a treatment with no active drug). But its not clear whether this side effect occurred in studies. It wasnt reported during studies of the drug. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. For more information on these side effects, see Side effect details below. Zetia is a brand-name prescription drug. Most patients will need at least 64 to 80 ounces (8 to 10 cups) of hydrating liquids throughout the day, such as water, broth, juice, or decaffeinated tea. Ask your doctor what other medications are better options for you. . muscle pain while taking ezetimibe with a statin. People with HoFH have high levels of LDL (bad) cholesterol. Zetia isnt a statin drug. Zetia belongs to a class of drugs called cholesterol absorption inhibitors. You can learn more about how we ensure our content is accurate and current by reading our. It belongs to a class of drugs called cholesterol absorption inhibitors. An allergic reaction is possible after using Zetia. POTS is a kind of dysautonomia or autonomic nervous disorder. Avoid eating foods high in fat or cholesterol, or Zetia will not be as effective. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Lipitor, or with both drugs (when taken individually). In the studies, total cholesterol levels: To learn how Zetia and the placebo affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. Twelve weeks of treatment with Zetia and atorvastatin or simvastatin was compared with atorvastatin or simvastatin used alone. Theyre a type of fat found in nuts, vegetable oils, and other plant-based foods. At the end of the study, researchers found that: Mixed hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol and fats are cleared from your body. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. If you have liver problems, your liver may not work properly to remove medications such as Zetia from your body. Porphyria patients are often overly sensitive to sunlight. The only FDA-approved dosage of Zetia for children is 10 mg once a day. Zetia is meant to be used in combination with a diet thats low in saturated fat and cholesterol. This included relief of muscle pain, muscle weakness, and cramps. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. Below are examples of these side effects. This is especially helpful to do when you first start taking new drugs or using a combination of treatments. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. Zetia generally costs more than Crestor. When taken together, it should be administered at least 2 hours before or 4 hours after a bile acid sequestrant. The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. The absence of symptoms doesn't necessarily mean that the cause of POTS is gone as well. (2018). Others may experience GI issues in conjunction with other symptoms, such as fainting. You may be more likely to develop this side effect if you take Zetia with a statin drug. You should take Zetia according to the instructions of your doctor or another healthcare professional. For more information, see the prescribing information for Zetia and Crestor. Zetia is FDA-approved to treat mixed high cholesterol when used with fenofibrate. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about the change in her physical appearance. However, you shouldnt stop taking Zetia without first talking with your doctor. POTS affects the body's ability to pump blood from the legs to the rest of the body while standing. Covers lawsuits, malpractice, class actions, fraud, legislation, regulation, enforcement. Variable: Generally it is well tolerated but common side effects include:muscle aches , abdominal discomfort / diarrhea, fatigue. If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. Most women describe brain zaps, also known as brain shivers or head shocks, as a repetitive electric-like sensation in the head. Sharing this information can help you avoid potential interactions. Increased liver enzymes can be a sign of liver damage. Diarrhea is a common side effect of Zetia. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. voice changes. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. As patients we need to be constantly wary because it is increasingly clear that the pharmas have abrogated their responsibility on our behalf. You may be able to find testimonials online from people who take Zetia. 2005-2023 Healthline Media a Red Ventures Company. Tell your doctor right away if you become pregnant while taking Zetia with a statin drug. Some may be a better fit for you than others. Cholesterol absorption inhibitors prevent your small intestine from absorbing cholesterol. For HoFH, Zetia is FDA-approved to decrease levels of total cholesterol and LDL cholesterol. If youre not sure if youll need to get prior authorization for Zetia, contact your insurance company. If you would like to report to the FDA a side effect youve had with Zetia, you can do so through MedWatch. The heart beats faster to pump it up to the brain, but with little success. If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. Talk with your doctor about the risks of taking Zetia with warfarin. In Zetia's clinical studies, these were some of the side effects that occurred more often: pain in the arms or legs. Currently, no medications have been approved by the FDA to treat POTS. Passes into breast milk pump blood from the legs to the brain, but little! With cholestyramine can decrease the amount of Zetia for children is 10 once. Become pregnant while taking Zetia with a low cholesterol/low fat diet and exercise to help cholesterol. Recommend that you take a supplement called coenzyme Q10 ( CoQ10 ) Zetia was compared with or! 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